Antibacterial Activities of a New Brominated Diterpene from Borneon Laurencia spp

نویسندگان

  • Charles Santhanaraju Vairappan
  • Takahiro Ishii
  • Tan Kai Lee
  • Minoru Suzuki
  • Zhan Zhaoqi
چکیده

In our continuous interest to study the diversity of halogenated metabolites of Malaysian species of the red algal genus Laurencia, we examined the chemical composition of five populations of unrecorded Laurencia sp. A new brominated diterpene, 10-acetoxyangasiol (1), and four other known metabolites, aplysidiol (2), cupalaurenol (3), 1-methyl-2,3,5-tribromoindole (4), and chamigrane epoxide (5), were isolated and identified. Isolated metabolites exhibited potent antibacterial activities against clinical bacteria, Staphylococcus aureus, Staphylococcus sp., Streptococcus pyogenes, Salmonella sp. and Vibrio cholerae.

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عنوان ژورنال:

دوره 8  شماره 

صفحات  -

تاریخ انتشار 2010